wound healing effect of an ointment made from a mixture of brassica oleracea var, punica granatum, and plantago major l extracts in rats

نویسندگان

mohammad hassan bazafkan department of environmental health engineering, school of health, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

ameneh hardani school of health, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; school of health, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-9354359475

mohammad reza afzal zadeh school of veterinary medicine, shahid chamran university, ahvaz, ir iran

ashraf amir zargar department of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

چکیده

results the average percentage of wound healing in different groups on days 3, 6, 9 and 12 were as follows; 21.3%, 37.87%, 67.39% and 77.17% in control group; 24.98%, 34.21%, 70.74% and 88.55% in positive control group; and 32.35%, 61.27%, 94.53%, and 99.91%, in case group. a significant difference was observed between the control and case groups (p < 0.05). conclusions treatment with the studied ointment could promote wound healing. materials and methods this experimental study was performed on 21 male wistar rats. firstly, a full thickness wound was created on rats flank, near the spine by a bistoury blade and forceps. then they were randomly divided into three groups of seven rats as the control group, a positive control group (the treatment group with phenytoin), and the third one received a treatment with studied ointment. the wounds were evaluated on days three, six, nine, and 12. results were compared by spss software using anova test. objectives the aim of the present study was to evaluate the effect of an ointment prepared from a mixture of cabbage, punica granatum, and plantago on local wound healing in wistar rats. background in iranian traditional medicine, punica granatum, cabbage, and plantago have been used to prompt wound healing. the effects of cabbage, punica granatum, and plantago in wound healing have been investigated to some extent, but no experimental study has been performed to assess the impact of an ointment containing all these three substances on wound healing.

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عنوان ژورنال:
jentashapir journal of health research

جلد ۵، شماره ۴، صفحات ۰-۰

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